BMC Medical Genomics
VOLUME 10 SUPPLEMENT 1
Selected articles from the 6th Translational Bioinformatics Conference (TBC 2016): medical genomics
Research
Publication of this supplement has not been supported by sponsorship. Information about the source of funding for publication charges can be found in the individual articles. The articles have undergone the journal's standard peer review process for supplements. The Supplement Editors declare that they have no competing interests.
Je Ju Island, Korea
15-17 October 2016
Edited by Ju Han Kim and Maricel Kann
Related articles have been published as a supplement to BMC Medical Informatics and Decision Making
- INTRODUCTIONBMC Medical Genomics 2017 10(Suppl 1):32Published on: 24 May 2017
- RESEARCH
N-of-1-pathways MixEnrich: advancing precision medicine via single-subject analysis in discovering dynamic changes of transcriptomes
Transcriptome analytic tools are commonly used across patient cohorts to develop drugs and predict clinical outcomes. However, as precision medicine pursues more accurate and individualized treatment decisions...BMC Medical Genomics 2017 10(Suppl 1):27Published on: 24 May 2017 - RESEARCH
Taking promoters out of enhancers in sequence based predictions of tissue-specific mammalian enhancers
Many genetic diseases are caused by mutations in non-coding regions of the genome. These mutations are frequently found in enhancer sequences, causing disruption to the regulatory program of the cell. Enhancer...BMC Medical Genomics 2017 10(Suppl 1):34Published on: 24 May 2017 - RESEARCH
A disease similarity matrix based on the uniqueness of shared genes
Complex diseases involve many genes, and these genes are often associated with several different illnesses. Disease similarity measurement can be based on shared genotype or phenotype. Quantifying relationship...BMC Medical Genomics 2017 10(Suppl 1):26Published on: 24 May 2017 - RESEARCH
Integrative information theoretic network analysis for genome-wide association study of aspirin exacerbated respiratory disease in Korean population
Aspirin Exacerbated Respiratory Disease (AERD) is a chronic medical condition that encompasses asthma, nasal polyposis, and hypersensitivity to aspirin and other non-steroidal anti-inflammatory drugs. Several ...BMC Medical Genomics 2017 10(Suppl 1):31Published on: 24 May 2017 - RESEARCH
Association analysis of rare variants near the APOE region with CSF and neuroimaging biomarkers of Alzheimer’s disease
The APOE ε4 allele is the most significant common genetic risk factor for late-onset Alzheimer’s disease (LOAD). The region surrounding APOE on chromosome 19 has also shown consistent association with LOAD. Howev...BMC Medical Genomics 2017 10(Suppl 1):29Published on: 24 May 2017 - RESEARCH
Identifying subtype-specific associations between gene expression and DNA methylation profiles in breast cancer
Breast cancer is a complex disease in which different genomic patterns exists depending on different subtypes. Recent researches present that multiple subtypes of breast cancer occur at different rates, and pl...BMC Medical Genomics 2017 10(Suppl 1):28Published on: 24 May 2017 - RESEARCH
Identification of epigenetic interactions between miRNA and DNA methylation associated with gene expression as potential prognostic markers in bladder cancer
One of the fundamental challenges in cancer is to detect the regulators of gene expression changes during cancer progression. Through transcriptional silencing of critical cancer-related genes, epigenetic chan...BMC Medical Genomics 2017 10(Suppl 1):30Published on: 24 May 2017
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