National Guideline Clearinghouse | AHRQ Evidence Reports

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National Guideline Clearinghouse | AHRQ Evidence Reports

Evidence Reports

The following provides a list of Evidence-Based Practice Center (EPC) reports starting with the most recent. These reports are used for informing and developing coverage decisions, quality measures, educational materials and tools, guidelines, and research agendas. For more information on EPCs including a list of archived reports, visit the AHRQs Web site.
209.   Closing Multigene Panels in Prostate Cancer Risk Assessment
208.   Closing the Quality Gap: Revisiting the State of the Science. The Patient-centered Medical Home
207.   Allocation of Scarce Resources During Mass Casualty Events
206.   Enabling Patient-Centered Care through Health Information Technology (Health IT)
205.   Diagnosis and Management of Febrile Infants (0–3 Months)
204.   An Evidence Review of Active Surveillance in Men With Localized Prostate Cancer
203.   Enabling Health Care Decisionmaking Through Clinical Decision Support and Knowledge Management
202.   Transition of Care for Acute Stroke and Myocardial Infarction Patients: From Hospitalization to Rehabilitation, Recovery, and Secondary Prevention
201.   Enabling Medication Management Through Health Information Technology (Health IT)
200.   Safety of Probiotics Used to Reduce Risk and Prevent or Treat Disease
199.   Health Literacy Interventions and Outcomes: An Updated Systematic Review
198.   Management of Acute Otitis Media: Update
197.   Alcohol Consumption and Cancer Risk: Understanding Possible Causal Mechanisms for Breast and Colorectal Cancers
196.   Assessment of Thiopurine Methyltransferase Activity in Patients Prescribed Azathioprine or Other Thiopurine-based Drugs: Addendum—Updating the Report and Reanalysis
195.   Inhaled Nitric Oxide in Preterm Infants
194.   Complementary and Alternative Therapies for Back Pain II
193.   Alzheimer's Disease and Cognitive Decline
192.   Lactose Intolerance and Health
191.   Vaginal Birth After Cesarean: New Insights
190.   Enhancing Use and Quality of Colorectal Cancer Screening
189.   Exercise-induced Bronchoconstriction and Asthma
188.   Impact of Consumer Health Informatics Applications
187.   Treatment of Overactive Bladder in Women
186.   Family History and Improving Health
185.   Diagnosis and Management of Ductal Carcinoma In Situ (DCIS)
184.   Treatment of Common Hip Fractures
183.   Vitamin D and Calcium: Systematic Review of Health Outcomes
181.   Outcomes of Community Health Worker Interventions
180.   Outcomes of Genetic Testing in Adults with a History of Venous Thromboembolism
179.   Clinical Utility of Cancer Family History Collection in Primary Care
177.   Complementary and Alternative Medicine in Back Pain Utilization
175.   Barriers and Drivers of Health Information Technology Use for the Elderly, Chronically Ill, and Underserved
174.   Management of Chronic Hepatitis B
173.   Integration of Mental Health/Substance Abuse and Primary Care
172.   HER2 Testing to Manage Patients with Breast or Other Solid Tumors
170.   Effectiveness of Weight Management Programs in Children and Adolescents
169.   Bariatric Surgery in Women of Reproductive Age: Special Concerns for Pregnancy
168.   Outcomes of Maternal Weight Gain
167.   Effectiveness of Assisted Reproductive Technology
166.   Diabetes Education for Children With Type 1 Diabetes Mellitus and Their Families
165.   Hydroxyurea for the Treatment of Sickle Cell Disease
164.   Utility of Monitoring Mycophenolic Acid in Solid Organ Transplant Patients
163.   Carbohydrate and Lipid Disorders and Relevant Considerations in Persons with Spinal Cord Injury
162.   Therapeutic Management, Delivery, and Postpartum Risk Assessment and Screening in Gestational Diabetes
161.   Prevention of Fecal and Urinary Incontinence in Adults
160.   Impact of Gene Expression Profiling Tests on Breast Cancer Outcomes
159.   Collection and Use of Cancer Family History in Primary Care
158.   Effectiveness and Safety of Vitamin D in Relation to Bone Health
157.   Treatment of Primary and Secondary Osteoarthritis of the Knee
156.   Antiretroviral (ARV) Drug Resistance in the Developing World
155.   Meditation Practices for Health: State of the Research
154.   Management of Uterine Fibroids: An Update of the Evidence
153.   Breastfeeding and Maternal and Infant Health Outcomes in Developed Countries
152.   Cardiac Resynchronization Therapy and Implantable Cardiac Defibrillators in Left Ventricular Systolic Dysfunction
151.   Nurse Staffing and Quality of Patient Care
150.   Hereditary Nonpolyposis Colorectal Cancer: Diagnostic Strategies and Their Implications
149.   Effectiveness of Continuing Medical Education
148.   The Uses of Heparin To Treat Burn Injury
147.   The Effectiveness of Different Methods of Toilet Training for Bowel and Bladder Control
146.   Testing for Cytochrome P450 Polymorphisms in Adults With Non-Psychotic Depression Treated With Selective Serotonin Reuptake Inhibitors (SSRIs)
145.   Genomic Tests for Ovarian Cancer Detection and Management
144.   Comparison of Endovascular and Open Surgical Repairs for Abdominal Aortic Aneurysm
143.   Management of Small Cell Lung Cancer
142.   Testing for BNP and NT-proBNP in the Diagnosis and Prognosis of Heart Failure
141.   Pediatric Anthrax: Implications for Bioterrorism Preparedness
140.   Tobacco Use: Prevention, Cessation, and Control
139.   Multivitamin/Mineral Supplements and Prevention of Chronic Disease
138.   Cancer Care Quality Measures: Diagnosis and Treatment of Colorectal Cancer
137.   Cancer Care Quality Measures: Symptoms and End of Life Care
136.   Value of the Periodic Health Evaluation
135.   Management of Eating Disorders
134.   B Vitamins and Berries and Age-Related Neurodegenerative Disorders
133.   Cesarean Delivery on Maternal Request
132.   Costs and Benefits of Health Information Technology
131.   Telemedicine for the Medicare Population—Update
130.   Management of Adnexal Mass
129.   Diagnosis and Management of Work-Related Asthma
128.   Diagnosis, Prognosis, and Therapy of Impaired Glucose Tolerance and Impaired Fasting Glucose
127.   Acute Stroke: Evaluation and Treatment
125.   Manifestations and Management of Chronic Insomnia in Adults
124.  Update on Acute Bacterial Rhinosinusitis
123.   Post-Myocardial Infarction Depression
122.   Knowledge and Access to Information on Recruitment of Underrepresented Populations to Cancer Clinical Trials
121.   Use of Spirometry for Case Finding, Diagnosis, and Management of Chronic Obstructive Pulmonary Disease (COPD)
117.   Effects of Omega-3 Fatty Acids on Eye Health
116.   Effects of Omega-3 Fatty Acids on Mental Health
115.   Effects of Omega-3 Fatty Acids on Organ Transplantation
114.   Effects of Omega-3 Fatty Acids on Cognitive Function with Aging, Dementia, and Neurological Diseases
113.   Effects of Omega-3 Fatty Acids on Cancer
111.   Wound-Healing Technologies: Low-Level Laser and Vacuum-Assisted Closure
110.   End-of-Life Care and Outcomes
108.   Melatonin for Treatment of Sleep Disorders
107.   Preventing Violence and Related Health-Risking Social Behaviors in Adolescents
106.   Cardiac Resynchronization Therapy for Congestive Heart Failure
104.   Celiac Disease
103.   Pharmacological and Surgical Treatment of Obesity
102.   Effectiveness of Behavioral Interventions to Modify Physical Activity Behaviors in General Populations and Cancer Patients and Survivors
101.   Economic Incentives for Preventive Care
100.   Criteria to Determine Disability Related to Multiple Sclerosis
99.   Community-Based Participatory Research
98.   Islet Transplantation in Patients with Type 1 Diabetes Mellitus
97.   Pharmacological Treatment of Dementia
96.   Regionalization of Bioterrorism Preparedness and Response
95.   Training of Hospital Staff To Respond to a Mass Casualty Incident
94.   Effects of Omega-3 Fatty Acids on Cardiovascular Disease
93.   Effects of Omega-3 Fatty Acids on Cardiovascular Risk Factors and Intermediate Markers of Cardiovascular Disease
92.   Effects of Omega-3 Fatty Acids on Arrhythmogenic Mechanisms in Animal and Isolated Organ/Cell Culture Studies
91.   Health Effects of Omega-3 Fatty Acids on Asthma
90.   Strategies for Improving Minority Healthcare Quality
89.   Effects of Omega-3 Fatty Acids on Lipids and Glycemic Control in Type II Diabetes and the Metabolic Syndrome and on Inflammatory Bowel Disease, Rheumatoid Arthritis, Renal Disease, Systemic Lupus Erythematosus, and Osteoporosis
88.   Effectiveness of Antimicrobial Adjuncts to Scaling and Root-Planing Therapy for Periodontitis
86.   Total Knee Replacement
85.   Hyperbaric Oxygen Therapy for Brain Injury, Cerebral Palsy, and Stroke
84.   Use of Glycated Hemoglobin and Microalbuminuria in the Monitoring of Diabetes Mellitus
79.   Diffusion and Dissemination of Evidence-based Cancer Control Interventions
78.   Best-Case Series for the Use of Immuno-Augmentation Therapy and Naltrexone for the Treatment of Cancer
77.   Management of Treatment-Resistant Epilepsy
76.   Ephedra and Ephedrine for Weight Loss and Athletic Performance Enhancement: Clinical Efficacy and Side Effects
74.   The Effect of Health Care Working Conditions on Patient Safety
73.   Criteria for Determining Disability in Infants and Children: Short Stature
72.   Criteria for Determining Disability in Infants and Children: Failure to Thrive
70.   Criteria for Determining Disability in Infants and Children: Low Birth Weight
69.   Management of Bronchiolitis in Infants and Children
68.   Diagnosis and Treatment of Deep Venous Thrombosis and Pulmonary Embolism
67.   Management of Allergic Rhinitis in the Working-Age Population
3.   Pharmacotherapy for Alcohol Dependence

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Evidence Technical Reviews

The following provides a list of Evidence-Based Practice Center (EPC) technical reviews starting with the most recent. For a list of archived reports, visit the Archived Technical Reviews on AHRQ's Web site.
17.   Nutritional Research Series

• Volume 1: Application of Systematic Review Methodology to the Field of Nutrition
• Volume 2: Issues and Challenges in Conducting Systematic Reviews to Support Development of Nutrient Reference Values: Workshop Summary
• Volume 3: Reporting of Systematic Reviews of Micronutrients and Health: A Critical Appraisal
• Volume 4: Effects of Eicosapentanoic Acid and Docosahexanoic Acid on Mortality Across Diverse Settings: Systematic Review and Meta-Analysis of Randomized Trials and Prospective Cohorts

16.   Updating Systematic Reviews
15.   Consumer-Oriented Strategies for Improving Health Benefit Design: An Overview
14.   A Critical Analysis of Care Coordination Strategies for Children With Special Health Care Needs
13.   Empirical Evaluation of the Association Between Methodological Shortcomings and Estimates of Adverse Events
12.   Criteria for Distinguishing Effectiveness From Efficacy Trials in Systematic Reviews
11.   Developing a Methodology for Establishing a Statement of Work for a Policy-Relevant Technical Analysis
10.   Strategies To Support Quality-based Purchasing
9.   Closing the Quality Gap:

• Volume 1: A Critical Analysis of Quality Improvement Strategies
• Volume 2: Diabetes Mellitus Care
• Volume 3: Hypertension Care
• Volume 4: Antibiotic Prescribing Behavior
• Volume 5: Asthma Care
• Volume 6: Healthcare-Associated Infections
• Volume 7: Care Coordination

8.   Meta-regression Approaches: What, Why, When, and How?
7.   Determinants of Increases in Medicare Expenditures for Physicians' Services
6.   Current Validity of AHRQ Clinical Practice Guidelines
5.   Measures of Patient Safety Based on Hospital Administrative Data—The Patient Safety Indicators
4.   Refinement of the HCUP Quality Indicators
3.   Diagnosis of Attention-Deficit/Hyperactivity Disorder
2.   Treatment of Headache

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Technology Assessment Reports

The technology assessment program at AHRQ provides technology assessments for the Centers for Medicare & Medicaid Services (CMS). These technology assessments are used by CMS to inform its national coverage decisions for the Medicare program as well as provide information to Medicare carriers. For a list of archived reports from 1990-2002, visit the AHRQ Web site . The AHRQ Web site also provides a list of Technology Assessments In Progress .
*Not available electronically. Contact AHRQTAP@ahrq.hhs.gov for report availability.
**Report is completed, but in the process of being prepared for posting. Please check back for updates.
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2011

• Outcomes of Sipuleucel-T Therapy

2010

• Bone Morphogenetic Protein: the State of the Evidence of On-Label and Off-Label Use
• Consideration of Evidence on Antiemetic Drugs for Nausea and Vomiting Associated with Chemotherapy or Radiation Therapy in Adults
• Diagnosis and Treatment of Secondary Lymphedema
• ECG-based Signal Analysis Technologies
• Genetic Tests for Non-cancer Diseases/Conditions: a Horizon Scan
• Quality, Regulation and Clinical Utility of Laboratory-developed Tests
• Comparative Evaluation of Radiation Treatments for Clinically Localized Prostate Cancer: an update
• Report on the Evidence Regarding Off-Label Indications for Targeted Therapies used in Cancer Treatment
• A Systematic Review of Loss-of-Heterozygosity Based Topographic Genotyping with PathfinderTG®***
• Systematic Reviews on Selected Pharmacogenetic Tests for Cancer Treatment: CYP2D6 for Tamoxifen in Breast Cancer, KRAS for anti-EGFR antibodies in Colorectal Cancer, and BCR-ABL1 for Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia

2009

• Reviews of Selected Pharmacogenetic Tests for Non-Cancer and Cancer Conditions

2008

• Evaluation of the Evidence on Benefits and Harms of Pulmonary Artery Catheter Use in Critical Care Settings
• Home Testing in Management of Chronic Diseases
• Horizon Scan of Invasive Interventions for Lower Extremity Peripheral Artery Disease and Systematic Review of Studies Comparing Stent Placement to Other Interventions
• Horizon Scan: Lipoprotein Subfractions for Identifying Patients at Increased Risks for Cardiovascular Diseases
• Methodological Issues in Evaluation of Innovative Training Approaches to Stroke Rehabilitation
• Non-Pharmacological Interventions for Post-Discharge Care in Heart Failure
• Positron Emission Tomography for Nine Cancers (Bladder, Brain, Cervical, Kidney, Ovarian, Pancreatic, Prostate, Small Cell Lung, Testicular)

2007

• Applicability of the Evidence Regarding Intensive Glycemic Control and Self-Monitored Blood Glucose to Medicare Patients with Type 2 Diabetes
• Compendia for Coverage of Off-Label Uses of Drugs and Biologics in an Anticancer Chemotherapeutic Regimen
• Cost-Effectiveness of DNA Stool Testing to Screen for Colorectal Cancer
• Decompression Therapy for the Treatment of Lumbosacral Pain
• Esophageal Doppler Ultrasound-based Cardiac Output Monitoring for Real-Time Therapeutic Management of Hospitalized Patients
• Genetic Tests for Non-Cancer Diseases/Conditions: A Horizon Scan
• Home Diagnosis of Obstructive Sleep Apnea-Hypopnea Syndrome
• Obstructive Sleep Apnea-Hypopnea Syndrome: Modeling Different Diagnostic Strategies
• Remote Cardiac Monitoring