Genomics|Update|Current: Infectious Diseases

Genomics|Update|Current

Infectious Diseases

Oral, capsulized, frozen fecal microbiota transplantation for relapsing clostridium difficile infection 
Ilan Youngster, et al. JAMA, October 11, 2014

Ebola virus disease in the Democratic Republic of Congo 
Gaël D. Maganga, et al. NEJM, October 15, 2014

UCSC Ebola genome browser now online to aid researchers' response to crisis, by Guy Lasnier, UCSC News, Oct 1

House fly genome deciphered in hunt for pest, pathogen control clues, GenomeWeb, Oct 14 [by free subscription only]

Research looks for genetic link to Valley Fever, by Alexandra Olgin, KJZZ, Oct 13

OMIC tools: A workflow for omic data analysis (NGS, microarray, PCR, MS, NMR)

OMICtools: an informative directory for multi-omic data analysis 
Henry VJ, et al. Database, Jul 2014.

Culture-independent diagnostic testing: have we opened Pandora's box for good? 
Janda JM, Abbott SA. Diag Microbiol Infect Dis 2014; 80(3): 171–176.

Leading the way: driving the delivery of pathogen genomics into practice, by Moorthie S, Luheshi L., PHG Foundation, Sep 2014

Bioinformatics tools extracted from a typical mammalian genome project, by Mangan M., OpenHelix blog post, Oct 6

New developments of RNAi in Paracoccidioides brasiliensis: prospects for high-throughput, genome-wide, functional genomics
Goes T, et al. PLoS Negl Trop Dis 2014; 8(10): e3173.

Resolution threshold of current molecular epidemiology of diphtheria 
Mokrousov I. Emerg Infect Dis, Nov 2014.

Evaluation of broad-range 16S rRNA PCR for the diagnosis of bloodstream infections: two years of experience
Hassan RM, et al. J Infect Dev Ctries 2014;8(10):1252-1258.

Recombination drives genome evolution in outbreak-related Legionella pneumophila isolates
Sanchez-Buso L, et al. Nat Genet, Oct 5, 2014.

Genomic surveillance elucidates Ebola virus origin and transmission during the 2014 outbreak
Gire SK, et al. Science 2014; 345: 1369-1372.

Portrait of a killer: genome of the 2014 EBOV outbreak strain 
Basler CF. Cell Host Microbe 2014; 16(4): 419–421.

Insights into the early epidemic spread of Ebola in Sierra Leone provided by viral sequence data 
Stadler T, et al. PLoS Curr (Outbreaks), Oct 6, 2014.

Molecular characterization of enteroviruses including a new type EV-C99 isolated from Xinjiang students in Shandong, China in 2011
Tao Z, et al. Sci Rep, Oct 9, 2014.

Nodding syndrome—a new hypothesis and new direction for research 
Colebunders R, et al. Int J Infect Dis 2014; 27: 74–77.

Genomic definition of hypervirulent and multidrug-resistant Klebsiella pneumoniae clonal groups 
Bialek-Davenet S, et al. Emerg Infect Dis, Nov 2014.

A delicate balance: maintaining mutualism to prevent disease 
Van Tyne D, et al. Cell Host Microbe 2014; 16(4): 425–427.

Re-appraisal of old and new diagnostic tools in the current management of chronic hepatitis B,  by Bessone F., Medscape [by free subscription only]

Reappraisal of known malaria resistance loci in a large multicenter study 
Malaria Genomic Epidemiology Network. Nat Genet, Sep 28, 2014.

Malaria severity influenced by five human genes, say researchers, by Paddock C., Medical News Today, Sep 29

Leishmania donovani infection causes distinct epigenetic DNA methylation changes in host macrophages
Marr AK, et al. PLoS Pathog 10(10): e1004419.

A modified γ-retrovirus vector for X-linked severe combined immunodeficiency
Hacein-Bey-Abina S, et al. N Engl J Med 2014; 371:1407-1417.

Genomic pathogen surveillance in animals: An early warning system for future pandemics? By Dr Chris Rands, PHG Foundation, Oct 7