Genomics|Update|Current: Pathogen Genome Sequencing: Public Health Applications

Genomics|Update|Current

Pathogen Genome Sequencing: Public Health Applications

CDC Advanced Molecular Detection Initiative: Imagine doing a 10,000-piece jigsaw puzzle in the time it takes to finish a 100-piece puzzle. Apply that to infectious disease control, and that’s AMD at work. Now imagine putting together that 10,000-piece puzzle when key pieces are missing, disease is spreading, and people are dying. AMD gives CDC scientists the “key pieces” they need to protect people from ever-changing infectious disease threats

Genomic polish for shoe-leather epidemiology
Steven Y. C. Tong. Nature Reviews Microbiology 11, 8 (2013)

In Snow's footsteps: Commentary on shoe-leather and applied epidemiology 
Denise Koo and Stephen B. Thacker. Epidemiologic Reviews (2010)

Sherlock genomes — viral investigator
Sarah E. Smith & Rachael S. Wash Nature Reviews Microbiology 11, 150 (2013)

High-throughput bacterial genome sequencing: an embarrassment of choice, a world of opportunity. 
Nicholas J. Loman, et al. Nature Reviews Microbiology 10, 599-606 (2012)

Transforming clinical microbiology with bacterial genome sequencing
Xavier Didelot, et al. Nature Reviews Genetics 13, 601-612 (2012)

Bacterial genome sequencing in the clinic: bioinformatic challenges and solutions
W. Florian Fricke & David A. Rasko. Nature Reviews Genetics 15, 49-55 (2014)