Guided visual exploration of genomic stratifications in cancer : Nature Methods : Nature Publishing Group

Guided visual exploration of genomic stratifications in cancer : Nature Methods : Nature Publishing Group

Figure 1: Seamless integration of visual and computational components in the extended StratomeX tool.

In the StratomeX view (top) columns represent different stratifications, each of which are divided into patient sets, and the bands between the columns represent the patients in the intersection of the connected sets. The wider the ban…

Guided visual exploration of genomic stratifications in cancer

• Marc Streit,
• Alexander Lex,
• Samuel Gratzl,
• Christian Partl,
• Dieter Schmalstieg,
• Hanspeter Pfister,
• Peter J Park
• & Nils Gehlenborg

• Affiliations
• Corresponding authors

Nature Methods

 

11,

 

884–885

 

(2014)

 

doi:10.1038/nmeth.3088

Published online

 

28 August 2014

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To the Editor:

Cancer is a heterogeneous disease, and molecular profiling of tumors from large cohorts has enabled characterization of new tumor subtypes. This is a prerequisite for improving personalized treatment and ultimately achieving better patient outcomes. Potential tumor subtypes can be identified with methods such as unsupervised clustering¹ or network-based…