Genomics|Update|Current: CANCER

Genomics|Update|Current

Cancer

Characteristics of individuals with breast cancer rearrangements in BRCA1 and BRCA2 
Jackson SA, et al. Cancer 2014 Feb

Contralateral mastectomy and survival after breast cancer in carriers of BRCA1 and BRCA2 mutations: retrospective analysis 
Metcalfe K, et al. BMJ 2014;348:g226

Determinants of genetic counseling uptake and its impact on breast cancer outcome: a population-based study 
Ayme A, et al. Breast Cancer Res Treat 2014 Feb

Fine-mapping the HOXB region detects common variants tagging a rare coding allele: Evidence for synthetic association in prostate cancer
Edward J. Saunders, et al.  PLOS Genetics 10(2): e1004129

Prostate cancer study suggests synthetic association between common SNPs and rarer causal variant, Genome Web, Feb 14 [by free subscription only]

Lynch Syndrome from a surgeon perspective: retrospective study of clinical impact of mismatch repair protein expression analysis in colorectal cancer patients less than 50 years old 
Baiocchi GL, et al. BMC Surg 2014 Feb;14(1):9

Patient-reported disease knowledge and educational needs in Lynch syndrome: findings of an interactive multidisciplinary patient conference.
Bannon SA, et al.  Hered Cancer Clin Pract. 2014 Feb 5;12(1):1.

Screening colonoscopy in first-degree relatives of patients with colorectal cancer 
Barzin G, et al. Arch Iran Med 2014 Feb;17(2):115-7

Targeted prostate cancer screening in BRCA1 and BRCA2 mutation carriers: Results from the initial screening round of the IMPACT Study.
Bancroft EK, et al.  Eur Urol. 2014 Jan 15.

Gene test helps patients avoid thyroid surgery. A molecular diagnosis gives doctors and patients better treatment options when suspicious lumps are found in the neck, by Susan Young, Tech Review, Feb 18

Seeking medical clues from the 'super responder', Frank Diamond, the Inquirer, Feb 16

If it works, new approach to detecting cancer may save your life, Christina Farr, Venture Beat, Feb 15

Nothing prepared me for cancer: My first diagnosis of cancer came at age 29. After the second diagnosis 7 years later, I thought, this time I could die, by Suzann Vera, ASCO Post Feb 15

Women with breast cancer gene mutation more likely to survive cancer after double mastectomy, Youtube video, Feb 13