The Agency for Healthcare Research and Quality's (AHRQ) Technology Assessment Program will be posting 2 Topic Refinement draft key question documents for review on February 14, 2014. The topic refinements are entitled “Use of Cardiac Resynchronization Therapy in the Medicare Population” and “Pain Management Injection Therapies for Low-back Pain.” If you are interested in reviewing either of these documents, please visit:http://www.ahrq.gov/research/
Public Review: Available Now
Topic Refinements Available for Review:
Pain Management Injection Therapies for Low-back Pain
Available: February 14 to March 3, 2014
Use of Cardiac Resynchronization Therapy in the Medicare Population
Available: February 14 to March 3, 2014
Pain Management Injection Therapies for Low-back Pain
Available: February 14 to March 3, 2014
Use of Cardiac Resynchronization Therapy in the Medicare Population
Available: February 14 to March 3, 2014
Technology Assessments
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The Technology Assessment (TA) Program at the Agency for Healthcare Research and Quality (AHRQ) provides technology assessments for the Centers for Medicare & Medicaid Services (CMS). These technology assessments are used by CMS to inform its national coverage decisions for the Medicare program as well as provide information to Medicare carriers.
- Public Review
- Technology Assessments Completed
- Technology Assessments in Progress
- Technology Assessment Archive
- Topic Refinements in Progress
AHRQ's TA Program uses state-of-the-art methodologies for assessing the clinical utility of medical interventions. Technology assessments are based on a systematic review of the literature, along with appropriate qualitative and quantitative methods of synthesizing data from multiple studies.
Technology assessments may be done in-house by AHRQ staff, or they may be done in collaboration with one of ourEvidence-based Practice Centers. When available, technology assessment topics are linked to corresponding information on the CMS Web site. For additional information, please contact the Technology Assessment Program atAHRQTAP@ahrq.hhs.gov.
Potential TA topics may go through a formal AHRQ Topic Refinement process. When CMS requests a Topic Refinement, the potential TA’s key questions and overall scope are reviewed by invited stakeholders, and the resulting document is posted for public comment.
Public Review
To get complete public review, the AHRQ TA Program will post draft reports on the AHRQ TA Web site. To meet the timelines for Medicare coverage decisions mandated by the Medicare Prescription Drug, Improvement, and Modernization Act of 2003, draft technology assessment reports will be available for public review for a limited time. A notice will be sent out on the CMS Medicare Coverage and AHRQ Effective Health Care Email distribution lists 1 week before the posting of draft reports. Each report will be available for public review on this Web site for a total of 2 weeks.
The AHRQ TA Program supports and is committed to the transparency of its review process. Therefore, starting March 18, 2009, invited peer review comments and public review comments will be publicly posted on the TA Program Web site within 3 months after the associated final report is posted on this Web site. The report authors' responses to the comments (the "disposition of comments") will be posted on the same Web page as the associated comments.
If topics undergo a formal Topic Refinement, the Topic Refinement document containing the scope of the potential TA will be posted on the AHRQ TA Web site for 2 weeks for public comment. Once public comments have been considered and revisions have been completed, the final Topic Refinement document will be posted on the AHRQ Web site.
Technology Assessments Completed
2013
- Assessment on Implantable Defibrillators and the Evidence for Primary Prevention of Sudden Cardiac Death
Disposition of Comments [ PDF File—722 KB] - Fluorescence In Situ Hybridization (FISH) or Other In Situ Hybridization (ISH) Testing of Uterine Cervical Cells to Predict Precancer and Cancer
Disposition of Comments - Skin Substitutes for Treating Chronic Wounds: Final Report [ PDF File—1.4 MB]
Disposition of Comments [ PDF File—1.89 MB] - Technology Assessment on Genetic Testing or Molecular Pathology Testing of Cancers with Unknown Primary Site to Determine Origin
Disposition of Comments [ PDF File—520 KB] - Update on Genetic Tests Currently Available for Clinical Use in Common Cancers
Disposition of Comments [ PDF File—292 KB]
2012
- The Impact of Pre-transplant Red Blood Cell Transfusions in Renal Allograph Rejection
Disposition of Comments - Management of Asymptomatic Carotid Stenosis [ PDF File—1.7 MB]
Disposition of Comments - Measuring Health-Related Quality of Life for Patients with Diabetic Retinopathy
Disposition of Comments - Systematic Review of Decision Tools and their Suitability for Patient-Centered Decisionmaking regarding Electronic Cardiac Device
- Systematic Review of ECG-based Signal Analysis Technologies for Evaluating Patients With Acute Coronary Syndrome
Disposition of Comments - Update on Mapping the Landscape of Genetic Tests for Non-Cancer Diseases/Conditions
Disposition of Comments
2011
- Effectiveness of Cochlear Implants in Adults with Sensorineural Hearing Loss
Disposition of Comments - Health Risk Appraisal
Disposition of Comments - Lifestyle Interventions for Four Conditions: Breast Cancer, Prostate Cancer, Type 2 Diabetes Mellitus, and Metabolic Syndrome
Disposition of Comments - Outcomes of Sipuleucel-T Therapy
Disposition of Comments - Update of Horizon Scans of Genetic Tests Currently Available for Clinical Use in Cancers
Disposition of Comments
2010
- Bone Morphogenetic Protein: The State of the Evidence for On-Label and Off-Label Use
Disposition of Comments - Consideration of Evidence on Antiemetic Drugs for Nausea and Vomiting Associated with Chemotherapy or Radiation Therapy
Disposition of Comments - Diagnosis and Treatment of Secondary Lymphedema
Disposition of Comments - ECG-based Signal Analysis Technologies
Disposition of Comments - Genetic Tests for Non-Cancer Diseases/Conditions: A Horizon Scan (Updated)
Disposition of Comments - Quality, Regulation and Clinical Utility of Laboratory-developed Molecular Tests (Corrected Final Report)
Errata (PDF File, 94 KB)
Disposition of Comments - Radiation Therapy for Localized Prostate Cancer: An Update
Disposition of Comments - Report on the Evidence Regarding Off-Label Indications for Targeted Therapies used in Cancer Treatment
Disposition of Comments - A Systematic Review of Loss-of-Heterozygosity Based Topographic Genotyping with PathfinderTG® (PDF File, 400 KB)
Disposition of Comments - Systematic Reviews on Selected Pharmacogenetic Tests for Cancer Treatment: CYP2D6 for Tamoxifen in Breast Cancer, KRAS for anti-EGFR antibodies in Colorectal Cancer, and BCR-ABL1 for Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia
Disposition of Comments
2009
- Cost-Effectiveness of CT Colonography to Screen for ColorectalCancer
- Horizon Scan: To What Extent Do Changes In Third-Party Payment Affect Clinical Trials And The Evidence Base?(PDF File, 520 KB)
- Negative Pressure Wound Therapy Devices
Disposition of Comments - Reviews of Selected Pharmacogenetic Tests for Non-Cancer and Cancer Conditions
- Use of Bayesian Techniques in Randomized Clinical Trials: A CMS Case Study
Disposition of Comments - White Paper: Potential Conflict of Interest in the Production of Drug Compendia
* Not available electronically. Contact AHRQTAP@ahrq.hhs.gov for report availability.
** Report is completed, but in the process of being prepared for posting. Please check back for updates.
Technology Assessments in Progress
Projects in final production phase (post-review)
- Cardiovascular Procedures and Subsequent Cognitive Function
- Genetic Testing for Risk of Recurrent Cancer
- Spinal Fusion for the Treatment of Low Back Pain Secondary to Lumbar Degenerative Disc Disease (Draft)***
Projects in early-mid production phase (pre-review)
- The Effectiveness of Hyaluronic Acid in the Treatment of Severe Degenerative Joint Disease (DJD) of the Knee
- Negative Pressure Wound Therapy Technologies
*** An updated report is being completed by the Effective Health Care Program and will be available when finished athttp://effectivehealthcare.ahrq.gov/index.cfm/search-for-guides-reviews-and-reports/?pageaction=displaytopic&topicid=410.
Technology Assessment Archive
Technology Assessments for 1990-2008These technology assessments were completed at least 4 years ago, and some as many as 20 years ago. These assessments may be outdated due to more recent research findings not included in the assessments and should be viewed cautiously in current medical practice. They are maintained for archival purposes only.
Topic Refinements in Progress
- Catheter Ablation for Atrial Fibrillation—Under Review (Comment period completed).
- Pain Management Injection Therapies for Low-Back Pain—Available for review soon.
- Therapeutic Options for Obesity in the Medicare Population
- Use of Cardiac Resynchronization Therapy in the Medicare Population—Available for review soon.
Current as of February 2014
Internet Citation: Technology Assessments. February 2014. Agency for Healthcare Research and Quality, Rockville, MD. http://www.ahrq.gov/research/findings/ta/index.html
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