Genomics|Update|Current ► Cancer

Genomics|Update|Current

Cancer

Adherence patterns to National Comprehensive Cancer Network guidelines for referral of women with breast cancer to genetics professionals 
Stuckey A, et al. Am J Clin Oncol 2014 Apr

An ultrasensitive method for quantitating circulating tumor DNA with broad patient coverage
Aaron M Newman et al Nature, April 6, 2014

Cancer therapy resistance: chasing epigenetics
Nature Medicine, April 7, 2014

Cost effectiveness of a 92-gene assay for the diagnosis of metastatic cancer 
Bentley TG, et al. J Med Econ 2014 Apr

Cost-effectiveness of a 14-gene risk score assay to target adjuvant chemotherapy in early stage non-squamous non-small cell lung cancer 
Roth JA, et al. Oncologist 2014 Apr

Epidermal growth factor receptor tyrosine kinase inhibitors vs conventional chemotherapy in non–small cell lung cancer harboring wild-type epidermal growth factor receptor - a meta-analysis
Lee J, et al. JAMA. 2014;311(14):1430-1437

From observation to intervention: Development of a psychoeducational intervention to increase uptake of BRCA genetic counseling among high-risk breast cancer survivors 
Vadaparampil ST, et al. J Cancer Educ 2014 Apr

Linkage of DNA methylation quantitative trait loci to human cancer risk.
Heyn H,et al. Cell Rep. 2014 Apr 2. pii: S2211-1247(14)00194-6.

Long-term satisfaction and quality of life following risk reducing surgery in BRCA1/2 mutation carriers 
Hooker GW, et al. Hered Cancer Clin Pract 2014 Apr;12(1):9

Prospective multicenter study of the impact of Oncotype DX colon cancer assay results on treatment recommendations in stage II colon cancer patients 
Srivastava G, et al. Oncologist 2014 Apr

To foster screening, new colon cancer tests emphasize convenience. 
Cassandra Willyard, Nature Medicine, April 7, 2014 

The landscape of somatic mutations in epigenetic regulators across 1,000 paediatric cancer genomes
Huether R, et al. Nat Commun. 2014 Apr 8;5:3630.

Validation of the Manchester scoring system for predicting BRCA1/2 mutations in 9,390 families suspected of having hereditary breast and ovarian cancer 
Kast K, et al. Int J Cancer 2014 Apr

Sidestepping the biopsy with new tools to spot cancer, by Andrew Pollack, New York Times, Apr 7

TCGA and its vital role in understanding how germline variation informs the landscape of somatic alterations in cancer, Stephen Chanock, NCI, Apr 2

TCGA's Pan-Cancer efforts and expansion to include whole genome sequence, Carolyn Hutter, NCI, Apr 1