June 23-30, 2016
Advanced Molecular Detection Clips
About Advanced Molecular Detection Clips
Clips are selected weekly from a variety of sources, including PubMed, journal tables of contents, and online media. Special emphasis is given to the use of next-generation genetic sequencing in infectious disease public health surveillance, investigation, and development of new diagnostics and interventions. The collection is not comprehensive but aims to capture highlights, while surveying a wide range of topics. CDC-authored articles are flagged. Items marked I&E address aspects of implementation or evaluation in clinical or public health practice.
Advanced Molecular Detection Clips Content
NEWS
- Experimental Zika vaccine is approved for clinical trials for first time in US
Branswell H. STAT, Jun 20, 2016. - Nucleic acid test deployed to screen donor blood supply for Zika in US
Healio, Jun 17, 2016. - 20th Anniversary of PulseNet: the National Molecular Subtyping Network for Foodborne Disease Surveillance — United States, 2016
MMWR, Jun 24, 2016 / 65(24);636. - Johns Hopkins Team Demonstrates Feasibility of Metagenomic Sequencing to Diagnose Brain Infections
Heger M. GenomeWeb, Jun 23, 2016. - CDC: Source of E. anophelis outbreak still unknown
Healio, Jun 20, 2016. - C. difficile patients diagnosed with PCR, NAATs more often receive prompt treatment
Healio, Jun 18, 2016. - UCSD Team Wins $9.5M NIH Grant to Use Systems Biology to Tackle Antibiotic Resistance
Macron D. GenomeWeb, Jun 15, 2016. - Seagulls Are Carrying a Dangerous Superbug Through the Skies
McKenna M. Nat Geo, Jun 22, 2016.
EVENTS / TRAINING / WEB RESOURCES
- Molecular Diagnostics for Infectious Disease
(conference) Next Generation Dx Summit, Aug 24-25, 2016, Washington, DC. - Nature Web Collection on Antimicrobial Resistance
Nature, Jun 2016. - Training in High-Throughput Sequencing: Common Guidelines to Enable Material Sharing, Dissemination, and Reusability.
Schiffthaler Bastian et al. PLoS computational biology 2016 Jun (6) e1004937 - High-throughput Sequencing (HTS) Training Repository
(online training materials) HTS Teachers' Consortium.
CONCEPTS / COMMENTS
- The Future of Whole Genome Sequencing for public health and the clinic.
Allard Marc W et al. Journal of clinical microbiology 2016 Jun - Taking forward a 'ONE HEALTH' approach for turning the tide against The Middle East Respiratory Syndrome Coronavirus and other zoonotic pathogens with epidemic potential.
Zumla Alimuddin et al. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 2016 Jun - The arsenal of pathogens and antivirulence therapeutic strategies for disarming them.
Brannon John R et al. Drug design, development and therapy 2016 1795-806 - Timing is Everything - Shortcomings of Current HIV Diagnostics in the Early Treatment Era.
Keating Sheila M et al. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2016 Jun - Genomics in the battle against Zika virus
Genomics Education Program UK, Jun 21, 2016.
METHODS / TOOLS
- Compositional analysis: a valid approach to analyze microbiome high-throughput sequencing data.
Gloor Gregory B et al. Canadian journal of microbiology 2016 Apr 1-12 - Utility of algorithms for the analysis of integrated Salmonella surveillance data.
Vrbova L et al. Epidemiology and infection 2016 Jul (10) 2165-75
EVOLUTION / ECOLOGY / POPULATIONS
- Whole genome sequencing as a tool for phylogenetic analysis of clinical strains of Mitis group streptococci.
Rasmussen L H et al. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 2016 Jun - Molecular survey of arthropod-borne pathogens in sheep keds (Melophagus ovinus), Central Europe.
Rudolf Ivo et al. Parasitology research 2016 Jun
- Complete Genome Sequences of Four Strains from the 2015-2016 Elizabethkingia anophelis Outbreak.
Nicholson Ainsley C et al. Genome announcements 2016 (3) - Phylodynamics of influenza A(H3N2) in South America, 1999-2012.
Born Priscila Silva et al. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2016 Jun 312-320 - Distribution of Marburg virus in Africa: An evolutionary approach.
Zehender Gianguglielmo et al. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2016 Jun 8-16 - Genetic Diversity and Reassortment of Hantaan Virus Tripartite RNA Genomes in Nature, the Republic of Korea.
Kim Jeong-Ah et al. PLoS neglected tropical diseases 2016 Jun (6) e0004650 - Viral nucleic acids in human plasma pools.
Zhang Wen et al. Transfusion 2016 Jun - Evolution, antigenicity and pathogenicity of global porcine epidemic diarrhea virus strains.
Lin Chun-Ming et al. Virus research 2016 Jun - Discovery of Point Mutations in the Voltage-Gated Sodium Channel from African Aedes aegypti Populations: Potential Phylogenetic Reasons for Gene Introgression.
Kawada Hitoshi et al. PLoS neglected tropical diseases 2016 Jun (6) e0004780 - Full-Length Venom Protein cDNA Sequences from Venom-Derived mRNA: Exploring Compositional Variation and Adaptive Multigene Evolution.
Modahl Cassandra M et al. PLoS neglected tropical diseases 2016 Jun (6) e0004587
PATHOGENICITY / ANTIMICROBIAL RESISTANCE
- Chromosomal Locations of mcr-1 and blaCTX-M-15 in Fluoroquinolone-Resistant Escherichia coli ST410.
Falgenhauer Linda et al. Emerging infectious diseases 2016 Sep (9) - CRISPR-Cas and Restriction-Modification Act Additively against Conjugative Antibiotic Resistance Plasmid Transfer in Enterococcus faecalis.
Price Valerie J et al. mSphere (3) - Circulation of a Quorum-Sensing-Impaired Variant of Vibrio cholerae Strain C6706 Masks Important Phenotypes.
Stutzmann Sandrine et al. mSphere (3) - Clonal diversity and epidemiological characteristics of Staphylococcus aureus: high prevalence of oxacillin-susceptible mecA-positive Staphylococcus aureus (OS-MRSA) associated with clinical isolates in Brazil.
Andrade-Figueiredo Mariana et al. BMC microbiology 2016 (1) 115 - Determination of the complete genome and functional analysis of HPV6 isolate VBD19/10 from a patient with aggressive recurrent respiratory papillomatosis.
Seedat R Y et al. Epidemiology and infection 2016 Jul (10) 2128-35 - Report of a novel c1483w mutation in the hepatitis e virus polymerase in patients with acute liver failure.
Borkakoti Jayanta et al. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2016 Jun - A Worldwide Map of Plasmodium falciparum K13-Propeller Polymorphisms.
Ménard Didier et al. The New England journal of medicine 2016 Jun (25) 2453-2464
DETECTION / DIAGNOSIS
- Mass spectrometry methods for predicting antibiotic resistance.
Charretier Yannick et al. Proteomics. Clinical applications 2016 Jun - Phenotypic H antigen typing by mass spectrometry combined with genetic typing of H antigens, O antigens, and toxins by whole genome sequencing (MS-H plus WGS-HOT) enhances the identification of E. coli isolates.
Cheng Keding et al. Journal of clinical microbiology 2016 Jun - Development of internally controlled duplex real-time NASBA diagnostics assays for the detection of microorganisms associated with bacterial meningitis.
Clancy Eoin et al. Journal of microbiological methods 2016 Jun - Changing Diagnostic Methods and Increased Detection of Verotoxigenic Escherichia coli, Ireland.
Rice Thomas et al. Emerging infectious diseases 2016 Sep (9) - Next-generation sequencing in neuropathologic diagnosis of infections of the nervous system
Salzberg S, et al. Neuroimmunol Neuroinflamm, Jun 13, 2016. - Rickettsia sp. Strain Atlantic Rainforest Infection in a Patient from a Spotted Fever-Endemic Area in Southern Brazil.
Krawczak Felipe S et al. The American journal of tropical medicine and hygiene 2016 Jun - Screening of Blood Donations for Zika Virus Infection — Puerto Rico, April 3–June 11, 2016
Kuehnert MJ, et al. MMWR, Jun 17, 2016. - Genetic Characterization of a Panel of Diverse HIV-1 Isolates at Seven International Sites.
Hora Bhavna et al. PloS one 2016 (6) e0157340
- Surveillance for Emerging Diseases with Multiplexed Point-of-Care Diagnostics.
Deshpande Alina et al. Health security (3) 111-21 - Instrument-Free Point-of-Care Molecular Detection of Zika Virus.
Song Jinzhao et al. Analytical chemistry 2016 Jun - Using Multiplex Molecular Testing to Determine the Etiology of Acute Gastroenteritis in Children.
Nicholson Maribeth R et al. The Journal of pediatrics 2016 Jun - More parasitic myositis cases in humans in Australia, and the definition of genetic markers for the causative agents as a basis for molecular diagnosis.
Koehler Anson V et al. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2016 Jun
EPIDEMIOLOGY / OUTBREAKS / TRANSMISSION
- Two Linked Enteroinvasive Escherichia coli Outbreaks, Nottingham, UK, June 2014
Newitt S, et al. Emerg Infect Dis, Jul 2016. - Confirming Legionnaires’ disease outbreak by genome-based method, Germany, 2012. Emerg Infect Dis. 2016 Jul
Burckhardt F, et al. Emerg Infect Dis, Jul 2016. - A large outbreak of Campylobacter jejuni infection in a university college caused by chicken liver pâté, Australia, 2013.
Moffatt C R M et al. Epidemiology and infection 2016 Jun 1-8 - The Molecular and Spatial Epidemiology of Typhoid Fever in Rural Cambodia.
Pham Thanh Duy et al. PLoS neglected tropical diseases 2016 Jun (6) e0004785 - XDR-TB transmission in London: Case management and contact tracing investigation assisted by early whole genome sequencing.
Arnold Amber et al. The Journal of infection 2016 Jun - Prevalence of different HIV-1 subtypes in sexual transmission in China: a systematic review and meta-analysis.
Yuan R et al. Epidemiology and infection 2016 Jul (10) 2144-53 - Probable transfusion-transmitted Zika virus in Brazil.
Barjas-Castro Maria L et al. Transfusion 2016 Jun
ANTIMICROBIALS / VACCINES / INTERVENTIONS
- High-throughput sequencing and vaccine design.
Luciani F et al. Revue scientifique et technique (International Office of Epizootics) 2016 Apr (1) 53-65 - Reduction of antibiotic resistance genes in intestinal microbiota of recurrent Clostridium difficile patients after fecal microbiota transplantation.
Jouhten Hanne et al. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2016 Jun
HOST-MICROBE INTERACTIONS
- A Single Residue in Ebola Virus Receptor NPC1 Influences Cellular Host Range in Reptiles.
Ndungo Esther et al. mSphere (2) - Genetic dissection of Flaviviridae host factors through genome-scale CRISPR screens
Marceau CD, et al. Nature, Jun 17, 2016. - ZIKV - CDB: A Collaborative Database to Guide Research Linking SncRNAs and ZIKA Virus Disease Symptoms.
Pylro Victor Satler et al. PLoS neglected tropical diseases 2016 Jun (6) e0004817 - Mutation in West Nile Virus Structural Protein prM during Human Infection.
Lustig Yaniv et al. Emerging infectious diseases 2016 Sep (9) - A CRISPR screen defines a signal peptide processing pathway required by flaviviruses
Zhang R, et al. Nature, Jun 17, 2016.
Note: indicates that at least one CDC-affiliated author; indicates that the article addresses aspects of implementation or evaluation in clinical or public health practice.
Disclaimer: Articles listed in the Advanced Molecular Detection Clips are selected by the CDC Office of Public Health Genomics to provide current awareness of the scientific literature and news. Inclusion in the clips does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the Clips, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.
indicates that at least one CDC-affiliated author; indicates that the article addresses aspects of implementation or evaluation in clinical or public health practice.Disclaimer: Articles listed in the Advanced Molecular Detection Clips are selected by the CDC Office of Public Health Genomics to provide current awareness of the scientific literature and news. Inclusion in the clips does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the Clips, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.
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