lunes, 16 de abril de 2012

Decision analysis, economic evaluation, and newbor... [Genet Med. 2012] - PubMed - NCBI

Decision analysis, economic evaluation, and newbor... [Genet Med. 2012] - PubMed - NCBI

Genet Med. 2012 Apr 5. doi: 10.1038/gim.2012.24. [Epub ahead of print]

Decision analysis, economic evaluation, and newborn screening: challenges and opportunities.

Source

Child Health Evaluation and Research Unit, Division of General Pediatrics, University of Michigan, Ann Arbor, Michigan, USA.

Abstract

The number of conditions included in newborn screening panels has increased rapidly in the United States during the past decade, and many more conditions are under consideration for addition to state panels. The rare nature of candidate conditions for newborn screening makes their evaluation challenging. The scarcity of data on the costs of screening, follow-up, treatment, and long-term disability must be addressed to improve the evaluation process for nominated conditions. Decision analyses and economic evaluations can help inform policy decisions for newborn screening programs by providing a systematic approach to synthesizing available evidence and providing projected estimates of long-term clinical and economic outcomes when long-term data are not available. In this review, we outline the types of data required for the development of decision analysis and cost-effectiveness models for newborn screening programs and discuss the challenges faced when applying these methods in the arena of newborn screening to help inform policy decisions.Genet Med advance online publication 5 April 2012.

PMID:
22481131
[PubMed - as supplied by publisher]

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