lunes, 22 de julio de 2013

Consumer Preferences for the Predictive Geneti... [J Genet Couns. 2013] - PubMed - NCBI

Consumer Preferences for the Predictive Geneti... [J Genet Couns. 2013] - PubMed - NCBI

J Genet Couns. 2013 Jul 12. [Epub ahead of print]

Consumer Preferences for the Predictive Genetic Test for Alzheimer Disease.


University of Georgia Clinical and Administrative Pharmacy College of Pharmacy, 231 RC Wilson Pharmacy, Athens, GA, 30602, USA,


The purpose of this study was to assess consumer preferences for predictive genetic testing for Alzheimer disease in the United States. A rating conjoint analysis was conducted using an anonymous online survey distributed by Qualtrics® to a general population panel in April 2011 in the United States. The study design included three attributes: Accuracy (40 %, 80 %, and 100 %), Treatment Availability (Cure is available/Drug for symptom relief but no cure), and Anonymity (Anonymous/Not anonymous). A total of 12 scenarios were used to elicit people's preference, assessed by an 11-point scale. The respondents also indicated their highest willingness-to-pay (WTP) for each scenario through open-ended questions. A total of 295 responses were collected over 4 days. The most important attribute for the aggregate model was Accuracy, contributing 64.73 % to the preference rating. Treatment Availability and Anonymity contributed 20.72 % and 14.59 %, respectively, to the preference rating. The median WTP for the highest-rating scenario (Accuracy 100 %, a cure is available, test result is anonymous) was $100 (mean = $276). The median WTP for the lowest-rating scenario (40 % accuracy, no cure but drugs for symptom relief, not anonymous) was zero (mean = $34). The results of this study highlight attributes people find important when making the hypothetical decision to obtain an AD genetic test. These results should be of interests to policy makers, genetic test developers and health care providers.
[PubMed - as supplied by publisher]

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