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Healthcare utilization and comorbidity burden amon... [J Pediatr. 2012] - PubMed - NCBI

Healthcare utilization and comorbidity burden amon... [J Pediatr. 2012] - PubMed - NCBI

J Pediatr. 2012 Oct;161(4):662-670.e2. doi: 10.1016/j.jpeds.2012.03.045. Epub 2012 May 10.

Healthcare utilization and comorbidity burden among children and young adults in the United States with systemic lupus erythematosus or inflammatory bowel disease.


RTI Health Solutions, Research Triangle Park, NC 27709-2194, USA. sjkarve@rti.org



We sought to assess the feasibility of using a health insurance claims database to estimate the prevalence and health care utilization and costs among children diagnosed with systemic lupus erythematosus (SLE) and inflammatory bowel disease (IBD).


This was a retrospective analysis of the LifeLink insurance claims database for the years 2000-2006. Children (0-15 years) and young adults (16-25 years) with ≥ 2 diagnosis claims for SLE or IBD were selected as the 2 cohorts of interest. For each member of the SLE and IBD cohorts, 2 individuals were randomly selected for a matched comparison group. All the analyses were descriptive in nature, CI for differences between means and 2 proportions for measures including health care utilization, comorbidity burden were based on t tests and 2-group tests of proportions.


We identified 278 patients with SLE (prevalence estimate: 7.9 per/100000 population) and 1174 patients with IBD (33.2 per/100000 population). The mean annual total medical costs was substantially higher for the SLE (difference: $22223; 95% CI: $14961-$29485) and IBD (difference: $16238; 95% CI: $14395-$18082) cohorts compared with those of the comparator cohort. We observed higher comorbidity burdens in the SLE and IBD cohorts than we saw in the comparator cohort.


Administrative claims data can be a useful tool for assessing the comparative prevalence and associated resource utilization of rare conditions such as SLE and IBD.
Copyright © 2012 Mosby, Inc. All rights reserved.
[PubMed - indexed for MEDLINE]

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