Evidence-based interventions to reduce adverse events in hospitals: a systematic review of systematic reviews.

Zegers M, Hesselink G, Geense W, Vincent C, Wollersheim H. BMJ Open. 2016;6:e012555.

This review examined the evidence base for reducing adverse events in hospitals. Investigators found sufficient evidence to support implementation of certain types of interventions, such as rapid response teams to reduce cardiac arrest and mortality rates, bundles and checklists to mitigate hospital-acquired infections, and pharmacist interventions to decrease adverse drug events. However, the overall evidence base for many of the patient safety interventions used by hospitals is weak.

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